1. From the Richard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center (S.G., R.K.W.), and Brigham and Women’s Hospital (S.G.) — both in Boston; and the Cardiovascular Division, John T. Milliken Department of Medicine, School of Medicine, and the Center for Health Economics and Policy, Washington University in St. Louis, St. Louis (K.J.M.).