Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria-Reference-Cited by-同舟云学术

Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria

Published:2022-08-04 Issue:5 Volume:387 Page:397-407
ISSN:0028-4793
Container-title:New England Journal of Medicine
language:en
Short-container-title:N Engl J Med

Author:

Wu Richard L.¹,Idris Azza H.¹,Berkowitz Nina M.¹,Happe Myra¹,Gaudinski Martin R.¹^ORCID,Buettner Christian¹,Strom Larisa¹,Awan Seemal F.¹,Holman LaSonji A.¹,Mendoza Floreliz¹,Gordon Ingelise J.¹,Hu Zonghui¹,Campos Chagas Andrezza¹,Wang Lawrence T.¹,Da Silva Pereira Lais¹,Francica Joseph R.¹,Kisalu Neville K.¹,Flynn Barbara J.¹,Shi Wei¹,Kong Wing-Pui¹,O’Connell Sarah¹,Plummer Sarah H.¹,Beck Allison¹,McDermott Adrian¹,Narpala Sandeep R.¹,Serebryannyy Leonid¹,Castro Mike¹^ORCID,Silva Rosa¹,Imam Marjaan¹,Pittman Iris¹,Hickman Somia P.¹,McDougal Andrew J.¹,Lukoskie Ashly E.¹,Murphy Jittawadee R.¹,Gall Jason G.¹,Carlton Kevin¹,Morgan Patricia¹,Seo Ellie¹,Stein Judy A.¹,Vazquez Sandra¹,Telscher Shinyi¹,Capparelli Edmund V.¹,Coates Emily E.¹,Mascola John R.¹,Ledgerwood Julie E.¹,Dropulic Lesia K.¹,Seder Robert A.¹

Affiliation:

1. From the Vaccine Research Center (R.L.W., A.H.I., N.M.B., M.H., M.R.G., C.B., L. Strom, S.F.A., L.A.H., F.M., I.J.G., L.T.W., L.D.S.P., J.R.F., N.K.K., B.J.F., W.S., W.-P.K., S.O., S.H.P., A.B., A.M., S.R.N., L. Serebryannyy, M.C., R.S., M.I., I.P., S.P.H., A.J.M., A.E.L., J.G.G., K.C., P.M., E.S., J.A.S., S.V., S.T., E.E.C., J.R. Mascola, J.E.L., L.K.D., R.A.S.) and the Biostatistics Research Branch, Division of Clinical Research (Z.H.), National Institute of Allergy and Infectious Diseases, National...

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Massachusetts Medical Society

Subject

General Medicine

Link

http://www.nejm.org/doi/pdf/10.1056/NEJMoa2203067

Reference19 articles.

1. Global Malaria Programme. World malaria report 2021. Geneva: World Health Organization, 2021.

2. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

3. A Monoclonal Antibody for Malaria Prevention

4. Antibodies against Plasmodium falciparum malaria at the molecular level

5. Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

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