Tranexamic Acid for Trauma Patients — More Lives to Save and Outcomes to Consider
Author:
Affiliation:
1. From the Global Health Trials Group, Clinical Trials Unit, London School of Hygiene and Tropical Medicine, London.
Publisher
Massachusetts Medical Society
Subject
General Medicine
Link
http://www.nejm.org/doi/pdf/10.1056/NEJMe2305075
Reference9 articles.
1. Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
2. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
3. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
4. Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
5. Prehospital Tranexamic Acid for Severe Trauma
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1. Efficacy and safety of tranexamic acid in acute haemorrhage;BMJ;2024-01-04
2. The PATCH-Trauma Trial: Antifibrinolytics and Stanching the Blood Meridian in Trauma;Journal of Cardiothoracic and Vascular Anesthesia;2023-12
3. Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials;Annals of Emergency Medicine;2023-11
4. Dose Dependent Tranexamic Acid Blunting of Penumbral Leukocyte Mobilization and Blood Brain Barrier Permeability Following Traumatic Brain Injury: An In-vivo Murine Study;2023-10-31
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