Twice-Yearly Depemokimab in Severe Asthma with an Eosinophilic Phenotype

Author:

Jackson David J.1ORCID,Wechsler Michael E.1,Jackson Daniel J.1,Bernstein David1,Korn Stephanie1,Pfeffer Paul E.1ORCID,Chen Ruchong1,Saito Junpei1,de Luíz Martinez Gustavo1,Dymek Lucyna1,Jacques Loretta1,Bird Nicholas1,Schalkwijk Stein1,Smith Douglas1,Howarth Peter1,Pavord Ian D.1

Affiliation:

1. From Guy’s Severe Asthma Centre, Guy’s and St. Thomas’ NHS Foundation Trust, and the School of Immunology and Microbial Sciences, King’s College London (David J. Jackson), Barts Health NHS Trust (P.E.P.), and GSK (L.J., N.B., S.S., P.H.), London, and the Oxford Respiratory NIHR Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford (I.D.P.) — all in the United Kingdom; National Jewish Health, Denver (M.E.W.); the University of Wisconsin–Madison, Madison ...

Funder

GlaxoSmithKline

Publisher

Massachusetts Medical Society

Reference31 articles.

1. Characterisation of patients with severe asthma in the UK Severe Asthma Registry in the biologic era

2. Global Initiative for Asthma (GINA). Difficult-to-treat and severe asthma in adolescent and adult patients: diagnosis and management. August 2023 (https://ginasthma.org/wp-content/uploads/2023/09/GINA-Severe-Asthma-Guide-2023-WEB-WMS.pdf).

3. Type 2 inflammation in asthma and other airway diseases

4. Comprehensive Characterization of Difficult-to-Treat Asthma Reveals Near Absence of T2-Low Status

5. Interleukin-5 in the Pathophysiology of Severe Asthma

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