1. From the University of Toronto (D.S.L., S.E.S., M.E.F., P.C.A., S.P., P.C., R.M.I., S. Shadowitz, H.A., J.A.U., M.J.S., S.M., H.J.R.), the Ted Rogers Centre for Heart Research and the Peter Munk Cardiac Centre, University Health Network (D.S.L., M.E.F., J.A.U., H.J.R.), ICES (formerly the Institute for Clinical Evaluative Sciences) (D.S.L., P.C.A., A.C., P.C., J.F., J.A.U., M.J.S.), St. Michael’s Hospital and Li Ka Shing Knowledge Institute, Unity Health (S.E.S., C.F.), the Divisions of Cardiology (S.P.)...