1. From the Division of Medical Toxicology and the Department of Emergency Medicine, University of Massachusetts Medical School, Worcester (K.M.B.); the Departments of Medicine and Emergency Medicine, University of Colorado School of Medicine, and the Department of Medicine, Colorado School of Public Health — both in Aurora (J.B.); and the Division of General Internal Medicine and the Departments of Clinical Pharmacology and Toxicology and Medicine, University of Toronto, Toronto (D.N.J.).