A Randomized Trial of Nafamostat for Covid-19

Author:

Morpeth Susan C.12,Venkatesh Balasubramanian345,Totterdell James A.6,McPhee Grace M.7,Mahar Robert K.89,Jones Mark10,Bandara Methma7,Barina Lauren A.7,Basnet Bhupendra K.1112,Bowen Asha C.13,Burke Andrew J.1415,Cochrane Belinda1617,Denholm Justin T.718,Dhungana Ashesh19,Dore Gregory J.2021,Dotel Ravindra22,Duffy Eamon2324,Dummer Jack2526,Foo Hong27,Gilbey Timothy L.28,Hammond Naomi E.293031,Hudson Bernard J.32,Jha Vivekanand5,Jevaji Purnima R.33,John Oommen3435,Joshi Rajesh33,Kang Gagandeep36,Kaur Baldeep29,Kim Seungtaek37,Das Santa Kumar38,Lau Jillian S.Y.39,Littleford Roberta40,Marsh Julie A.1341,Marschner Ian C.42,Matthews Gail4344,Maze Michael J.45,McArthur Colin J.46,McFadyen James D.4748,McMahon James H.49,McQuilten Zoe K.5051,Molton James52,Mora Jocelyn M.7,Mudaliar Vijaybabu33,Nguyen Vi7,O’Sullivan Matthew V.N.5354,Pant Suman38,Park Jaha E.55,Paterson David L.56,Price David J.78,Raymond Nigel5758,Rees Megan A.59,Robinson James O.6061,Rogers Benjamin A.6263,Ryu Wang-Shick64,Sasadeusz Joe18,Shum Omar6566,Snelling Thomas L.613,Sommerville Christine7,Trask Nanette67,Lewin Sharon R.71849,Hills Thomas E.6869,Davis Joshua S.7071,Roberts Jason A.72737475,Tong Steven Y.C.718

Affiliation:

1. Department of Microbiology and Infectious Diseases, Middlemore Hospital, Te Whatu Ora Counties Makukau, Auckland, New Zealand

2. Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

3. Department of Intensive Care Medicine, The University of Queensland at Princess Alexandra Hospital, Woolloongabba, QLD, Australia

4. Department of Intensive Care Medicine, The University of Queensland at The Wesley Hospital, Toowong, QLD, Australia

5. The George Institute for Global Health, Newtown, NSW, Australia

6. Faculty of Medicine and Health, The University of Sydney School of Public Health, Sydney

7. Department of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia

8. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia

9. Clinical Epidemiology and Biostatistics Unit, Murdoch Children’s Research Institute, Melbourne, VIC, Australia

10. Department of Health and Clinical Analytics, The University of Sydney School of Public Health, Sydney

11. Department of Medicine, Bir Hospital, Kathmandu, Nepal

12. Department of Infectious Diseases, Perth Children’s Hospital, Perth, WA, Australia

13. Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, WA, Australia

14. Faculty of Medicine, The University of Queensland, Herston, QLD, Australia

15. Department of Infectious Diseases, Prince Charles Hospital, Merthyr Tydfil, United Kingdom

16. Department of Respiratory and Sleep Medicine, Campbelltown Hospital, Campbelltown, NSW, Australia

17. Western Sydney University School of Medicine, Campbelltown, NSW, Australia

18. Victorian Infectious Diseases Service, The Royal Melbourne Hospital, Melbourne, VIC, Australia

19. Department of Medicine, National Academy of Medical Sciences at Bir Hospital, Kathmandu, Nepal

20. Viral Hepatitis Clinical Research Program, Kirby Institute, University of New South Wales, Kensington, NSW, Australia

21. Department of Infectious Diseases, St. Vincent’s Hospital, Melbourne, VIC, Australia

22. Department of Infectious Diseases, Blacktown Hospital, Blacktown, NSW, Australia

23. Department of Infectious Diseases, Te Whatu Ora Health New Zealand at Auckland City Hospital, Auckland, New Zealand

24. School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

25. Department of Medicine, University of Otago, Dunedin, New Zealand

26. Respiratory Services, Dunedin Hospital, Dunedin, New Zealand

27. Department of Microbiology and Infectious Diseases, NSW Health Pathology Liverpool, Liverpool, NSW, Australia

28. Department of Medicine and Infectious Diseases, Wagga Wagga Base Hospital, Wagga Wagga, Australia

29. Critical Care Program, The George Institute for Global Health, New Town, NSW, Australia

30. Critical Care Program, The University of New South Wales, Sydney

31. Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, St. Leonards, NSW, Australia

32. Department of Microbiology and Infectious Diseases, NSW Health Pathology, St. Leonards, St. Leonards, NSW, Australia

33. Department of Research, The George Institute for Global Health, Pune, Maharashta, India

34. Department of Research, The George Institute for Global Health, Vellore, India

35. Prasanna School of Public Health, Manipal Academy of Higher Education, Karnataka, India

36. Wellcome Trust Research Laboratory, Chartered Accountants Australia and New Zealand, Sydney

37. Zoonotic Virus Laboratory, Institut Pasteur Korea, Bundang-gu, Gyeonggi-do, Republic of Korea

38. Department of Internal Medicine, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Nepal

39. Department of Infectious Diseases, Eastern Health, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia

40. UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Queensland, QLD, Australia

41. Centre for Child Health Research, University of Western Australia Medical School, Nedlands, WA, Australia

42. NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Sydney

43. Department of Infectious Diseases, St. Vincent’s Hospital Sydney, Sydney

44. Therapeutic and Vaccine Research Program, The Kirby Institute at The University of New South Wales, Kensington, NSW, Australia

45. Department of Medicine, University of Otago Christchurch, Christchurch, New England

46. Department of Critical Care Medicine, Te Whatu Ora — Health New Zealand, Wellington, New Zealand

47. Department of Clinical Haematology, Alfred Hospital, Melbourne, VIC, Australia

48. Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia

49. Department of Infectious Diseases, Alfred Health and Monash University, Melbourne, VIC, Australia

50. Department of Haematology, Monash Health, Melbourne, VIC, Australia

51. School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia

52. Department of Infectious Diseases, Western Health, Footscray, VIC, Australia

53. Department of Microbiology and Infectious Diseases, NSW Health Pathology Westmead Hospital, Newcastle, NSW, Australia

54. Faculty of Medicine and Health, University of Sydney Westmead Clinical School, Sydney

55. Business Development Team, Chong Kun Dang Pharmaceutical Corp., Dongbaekjukjeon-daero, Giheung-gu Yongin, Kyeonggi-do, Republic of Korea

56. Saw Swee Hock School of Public Health, National Institute of Singapore, Singapore

57. Department of Medicine, Te Whatu Ora Health New Zealand Capital, Coast and Hutt Valley, Wellington, New Zealand

58. Department of Medicine, Wellington School of Medicine, University of Otago, Wellington, New Zealand

59. Department of Respiratory and Sleep Medicine, The Royal Melbourne Hospital, Melbourne, VIC, Australia

60. Department of Infectious Diseases, Royal Perth Hospital, Perth, WA, Australia

61. Department of Microbiology, PathWest Laboratory Medicine, Nedlands, WA, Australia

62. Centre for Inflammatory Diseases, School of Clinical Sciences, Monash University, Clayton, VIC, Australia

63. Department of Infectious Diseases, Monash Health, Clayton, VIC, Australia

64. Virology, Institute Pasteur Korea, Bundang-gu, Gyeonggi-do, Republic of Korea

65. Department of Infectious Diseases, Wollongong Hospital, Kingoonya, NSW, Australia

66. Graduate School of Medicine, University of Wollongong, Wollonngong, NSW, Australia

67. Chartered Accountants Australia and New Zealand, Sydney

68. Department of Clinical Research, Medical Research Institute of New Zealand, Wellington, New Zealand

69. Department of Infectious Diseases, Auckland City Hospital, Auckland, New Zealand

70. School of Medicine and Public Health, The University of Newcastle, New Castle, Australia

71. Global and Tropical Health Division, Menzies School of Health Research, Darwin, NT, Australia

72. Faculty of Medicine, The University of Queensland Centre for Clinical Research, Herston, QLD, Australia

73. Metro North Health, Herston Infectious Diseases Institute, Herston, QLD, Australia

74. Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women’s Hospital, Herston, QLD, Australia

75. Division of Anaesthesiology, Critical Care Emergency and Pain Medicine, Nîmes University Hospital at The University of Montpellier, Nîmes, France

Publisher

Massachusetts Medical Society

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