Sounding Out the Blood–Brain Barrier
Author:
Affiliation:
1. From Sunnybrook Research Institute and the Department of Medical Biophysics and the Institute of Biomedical Engineering, University of Toronto — both in Toronto.
Publisher
Massachusetts Medical Society
Subject
General Medicine
Link
http://www.nejm.org/doi/pdf/10.1056/NEJMe2311358
Reference13 articles.
1. A Historical Review of Brain Drug Delivery
2. Ultrasound Blood–Brain Barrier Opening and Aducanumab in Alzheimer’s Disease
3. Aducanumab, gantenerumab, BAN2401, and ALZ-801—the first wave of amyloid-targeting drugs for Alzheimer’s disease with potential for near term approval
4. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles
5. Evaluation of permeability, doxorubicin delivery, and drug retention in a rat brain tumor model after ultrasound-induced blood-tumor barrier disruption
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