The Journey to RSV Vaccines — Heralding an Era of Structure-Based Design
Author:
Affiliation:
1. From the Departments of Medicine and of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta.
Publisher
Massachusetts Medical Society
Subject
General Medicine
Link
http://www.nejm.org/doi/pdf/10.1056/NEJMp2216358
Reference5 articles.
1. RESPIRATORY SYNCYTIAL VIRUS DISEASE IN INFANTS DESPITE PRIOR ADMINISTRATION OF ANTIGENIC INACTIVATED VACCINE12
2. Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus
3. A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism
4. Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors
5. A proof of concept for structure-based vaccine design targeting RSV in humans
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