Phase 3 Trial of mRNA-1273 during the Delta-Variant Surge-Reference-Cited by-同舟云学术

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Phase 3 Trial of mRNA-1273 during the Delta-Variant Surge

Published:2021-12-23 Issue:26 Volume:385 Page:2485-2487
ISSN:0028-4793
Container-title:New England Journal of Medicine
language:en
Short-container-title:N Engl J Med

Author:

Baden Lindsey R.¹,El Sahly Hana M.²,Essink Brandon³,Follmann Dean⁴,Neuzil Kathleen M.⁵,August Allison⁶,Clouting Heather⁶,Fortier Gabrielle⁶,Deng Weiping⁶,Han Shu⁶,Zhao Xiaoping⁶,Leav Brett⁶,Talarico Carla⁶,Girard Bethany⁶,Paila Yamuna D.⁶,Tomassini Joanne E.⁶,Schödel Florian⁶,Pajon Rolando⁶,Zhou Honghong⁶,Das Rituparna⁶,Miller Jacqueline⁶

Affiliation:

1. Brigham and Women’s Hospital, Boston, MA

2. Baylor College of Medicine, Houston, TX

3. Meridian Clinical Research, Omaha, NE

4. National Institute of Allergy and Infectious Diseases, Bethesda, MD

5. University of Maryland, Baltimore, MD

6. Moderna, Cambridge, MA

Funder

Office of the Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority

National Institute of Allergy and Infectious Diseases

Publisher

Massachusetts Medical Society

Subject

General Medicine

Link

http://www.nejm.org/doi/pdf/10.1056/NEJMc2115597

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1. Safety, immunogenicity and preliminary efficacy of a randomized clinical trial of omicron XBB.1.5-containing bivalent mRNA vaccine;hLife;2024-02

2. Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5;Vaccines;2023-12-28

3. Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models;Human Vaccines & Immunotherapeutics;2023-11-27

4. Effectiveness of the second COVID-19 booster against Omicron: a large-scale cohort study in Chile;Nature Communications;2023-10-27

5. Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates;Science Immunology;2023-10-27

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