1. From the Institute of Health Research, University of Exeter (S.E.L., C.H., R.S.), and Royal Devon and Exeter Hospital (R.S.), Exeter, the Warwick Clinical Trials Unit, Division of Health Sciences, University of Warwick (J.B., C.J., R. Lall, E.W., S.F., M.U.), and University Hospitals Coventry and Warwickshire (M.U.), Coventry, Leeds Institute of Health Sciences, University of Leeds, Leeds (R. Longo, C.B.), and the Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University...