Negative pressure wound therapy for management of the surgical incision in orthopaedic surgery

Author:

Karlakki S.1,Brem M.2,Giannini S.3,Khanduja V.4,Stannard J.5,Martin R.6

Affiliation:

1. Robert Jones Agnes Hunt Orthopaedic Hospital, Arthroplasty Department, Oswestry SY10 7AG, UK.

2. Klinikum Nuernberg, Department of Orthopaedic and Trauma Surgery, Friedrich-Alexander University Erlangen-Nuremberg, Bresslauerstr. 90419 Nuremberg, Germany.

3. Istituto Ortopedico Rizzoli, Clinica Ortopedica e Traumatologica II, Di Barbiano, 1/10, 40136 Bologna, Italy.

4. Addenbrookes Hospital, Department of Trauma and Orthopaedics, Cambridge CB2 0QQ, UK.

5. Missouri Orthopaedic Institute, Department of Orthopaedic Surgery, University of Missouri Healthcare, 1100 Virginia Avenue, Columbia, Missouri 65212, USA.

6. Smith & Nephew Ltd, Advanced Wound Devices, Advanced Wound Management Division, Hull HU3 2BN, UK.

Abstract

Objectives The period of post-operative treatment before surgical wounds are completely closed remains a key window, during which one can apply new technologies that can minimise complications. One such technology is the use of negative pressure wound therapy to manage and accelerate healing of the closed incisional wound (incisional NPWT). Methods We undertook a literature review of this emerging indication to identify evidence within orthopaedic surgery and other surgical disciplines. Literature that supports our current understanding of the mechanisms of action was also reviewed in detail. Results A total of 33 publications were identified, including nine clinical study reports from orthopaedic surgery; four from cardiothoracic surgery and 12 from studies in abdominal, plastic and vascular disciplines. Most papers (26 of 33) had been published within the past three years. Thus far two randomised controlled trials – one in orthopaedic and one in cardiothoracic surgery – show evidence of reduced incidence of wound healing complications after between three and five days of post-operative NPWT of two- and four-fold, respectively. Investigations show that reduction in haematoma and seroma, accelerated wound healing and increased clearance of oedema are significant mechanisms of action. Conclusions There is a rapidly emerging literature on the effect of NPWT on the closed incision. Initiated and confirmed first with a randomised controlled trial in orthopaedic trauma surgery, studies in abdominal, plastic and vascular surgery with high rates of complications have been reported recently. The evidence from single-use NPWT devices is accumulating. There are no large randomised studies yet in reconstructive joint replacement. Cite this article: Bone Joint Res 2013;2:276–84.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

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