Incidence of venous thromboembolism in elective foot and ankle surgery with and without aspirin prophylaxis

Author:

Griffiths J. T.1,Matthews L.1,Pearce C. J.2,Calder J. D. F.3

Affiliation:

1. Basingstoke and North Hampshire NHS Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, UK.

2. Jurong Health Alexandra Hospital, 378 Alexandra Road, 159964, Singapore.

3. Chelsea and Westminster Hospital NHS Foundation Trust, 369 Fulham Road, London SW10 9NA, UK.

Abstract

The incidence of deep-vein thrombosis (DVT) and pulmonary embolism (PE) is thought to be low following foot and ankle surgery, but the routine use of chemoprophylaxis remains controversial. This retrospective study assessed the incidence of symptomatic venous thromboembolic (VTE) complications following a consecutive series of 2654 patients undergoing elective foot and ankle surgery. A total of 1078 patients received 75 mg aspirin as routine thromboprophylaxis between 2003 and 2006 and 1576 patients received no form of chemical thromboprophylaxis between 2007 and 2010. The overall incidence of VTE was 0.42% (DVT, 0.27%; PE, 0.15%) with 27 patients lost to follow-up. If these were included to create a worst case scenario, the overall VTE rate was 1.43%. There was no apparent protective effect against VTE by using aspirin. We conclude that the incidence of VTE following foot and ankle surgery is very low and routine use of chemoprophylaxis does not appear necessary for patients who are not in the high risk group for VTE.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

Reference38 articles.

1. Hinchliffe D, Amess D, Austin J, et al. House of Commons Health Committee: the prevention of venous thromboembolism in hospitalised patients, 2005. http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/99/99.pdf (date last accessed 27 September 2011).

2. Prevention of Venous Thromboembolism

3. A Meta-analysis of Methods to Prevent Venous Thromboembolism Following Total Hip Replacement

4. Should symptomatic, isolated distal deep vein thrombosis be treated with anticoagulation?

5. MORTALITY AND FATAL PULMONARY EMBOLISM AFTER PRIMARY TOTAL HIP REPLACEMENT

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