1. Edinburgh University Department of Orthopaedic Surgery, New Royal Infirmary of Edinburgh, Little France, Edinburgh EH16 4SU, UK.
2. The Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford OX3 7BN, UK.
3. Nuffield Department of Orthopaedic Surgery, University of Oxford, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD, UK.