Antibiotic prophylaxis in orthopaedic surgery

Author:

Bryson D. J.1,Morris D. L. J.2,Shivji F. S.1,Rollins K. R.1,Snape S.3,Ollivere B. J.1

Affiliation:

1. Queen’s Medical Centre, Nottingham NG7 2UH, UK.

2. King’s Mill Hospital, Sutton-in-Ashfield, Nottinghamshire, NG17 4JL, UK.

3. Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Rd, Nottingham NG5 1PB, UK.

Abstract

Prophylactic antibiotics can decrease the risk of wound infection and have been routinely employed in orthopaedic surgery for decades. Despite their widespread use, questions still surround the selection of antibiotics for prophylaxis, timing and duration of administration. The health economic costs associated with wound infections are significant, and the judicious but appropriate use of antibiotics can reduce this risk. This review examines the evidence behind commonly debated topics in antibiotic prophylaxis and highlights the uses and advantages of some commonly used antibiotics. Cite this article: Bone Joint J 2016;98-B:1014–19.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

Reference76 articles.

1. Prevention of surgical site infections in orthopaedic surgery and bone trauma: state-of-the-art update

2. Prevention of Perioperative Infection

3. No authors listed. Antimicrobial resistance: global report on surveillance 2014. http://www.who.int/drugresistance/documents/surveillancereport/en/ (date last accessed 3 March 2016).

4. Prophylactic Antibiotics in Hip and Knee Arthroplasty

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