A MALIGNANT PERIPHERAL NERVE-SHEATH TUMOUR RESPONDING TO CHEMOTHERAPY-Reference-Cited by-同舟云学术

A MALIGNANT PERIPHERAL NERVE-SHEATH TUMOUR RESPONDING TO CHEMOTHERAPY

Published:2004-01 Issue:1 Volume:86-B Page:113-115
ISSN:0301-620X
Container-title:The Journal of Bone and Joint Surgery. British volume
language:en
Short-container-title:The Journal of Bone and Joint Surgery. British volume

Author:

Masui F.¹,Yokoyama R.²,Soshi S.¹,Beppu Y.²,Asanuma K.¹,Fujii K.¹

Affiliation:

1. Department of Orthopaedic Surgery, Jikei University School of Medicine, 3-25-8 Nishisinbashi, Minatoku, Tokyo 105-8461, Japan.

2. Orthopaedic Division, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Abstract

Amalignant peripheral nerve-sheath tumour developed in the right S1 nerve root in a man aged 30 causing back pain and sciatica. CT and MRI revealed a destructive tumour of the sacrum invading the retroperitoneal space. The tumour was not resectable with an adequate margin. Chemotherapy, consisting of high-dose ifosfamide followed by a combination of vincristine, doxorubicin and cyclophosphamide, was given with success. Malignant peripheral nerve-sheath tumours are thought to respond weakly to chemotherapy, but the response in our patient was complete.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

Link

https://online.boneandjoint.org.uk/doi/pdf/10.1302/0301-620X.86B1.14032

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