The surgical management of metastatic epidural compression of the spinal cord

Author:

Quraishi N. A.1,Gokaslan Z. L.2,Boriani S.3

Affiliation:

1. Centre for Spine Studies and Surgery, Queens Medical Centre, Derby Road, Nottingham NG7 2UH, UK.

2. Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 7-109 Baltimore, Maryland 21287, USA.

3. Rizzoli Institute, via Pupilli 1, 40136 Bologna, Italy.

Abstract

Metastatic epidural compression of the spinal cord is a significant source of morbidity in patients with systemic cancer. With improved oncological treatment, survival in these patients is improving and metastatic cord compression is encountered increasingly often. The treatment is mostly palliative. Surgical management involves early circumferential decompression of the cord with concomitant stabilisation of the spine. Patients with radiosensitive tumours without cord compression benefit from radiotherapy. Spinal stereotactic radiosurgery and minimally invasive techniques, such as vertebroplasty and kyphoplasty, with or without radiofrequency ablation, are promising options for treatment and are beginning to be used in selected patients with spinal metastases. In this paper we review the surgical management of patients with metastatic epidural spinal cord compression.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

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