Affiliation:
1. Department of Pathology
2. Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy.
Abstract
We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival. More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develope metastases or cause death, while grade 3 tumours had the worst outcome and prognosis. Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.
Publisher
British Editorial Society of Bone & Joint Surgery
Subject
Orthopedics and Sports Medicine,Surgery
Reference17 articles.
1. Primary chondrosarcoma of long bones and limb girdles
2. Miller RW, Boice JD Jr, Curtis RE. Bone cancer. In: Schottenfeld D, Fraumeni JF Jr, eds. Cancer epidemiology and prevention. Second edition. New York: Oxford University Press, 1996:971–83.
3. Larsson SE, Lorentzon R. The geographic variation of the incidence of malignant primary bone tumours in Sweden. J Bone Joint Surg [Am] 1974;56-A:592–600.
4. Unni KK. Dahlin’s bone tumors: general aspects and data on 11,087 cases. Fifth ed. Philadelphia: Lippincott-Raven, 1996:71–108.
5. Schajowicz F. Tumor and tumor like lesions of bone: pathology, radiology, and treatment. Second edition. Berlin: Springer-Verlag, 1994:141–244.
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