Surgical treatment and outcome of conventional pelvic chondrosarcoma

Author:

Donati D.1,Ghoneimy A. El2,Bertoni F.1,Di Bella C.1,Mercuri M.1

Affiliation:

1. Department of Pathology

2. Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, Italy.

Abstract

We reviewed 124 patients with a conventional pelvic chondrosarcoma who had been treated over a period of 20 years. We recorded the type of tumour (central or peripheral), type of operation (limb salvage surgery or hemipelvectomy), the grade of tumour, local recurrence and/or metastases, in order to identify the factors which might influence survival. More satisfactory surgical margins were achieved for central tumours or in those patients treated by hemipelvectomy. However, grade 1 tumours, whatever the course, did not develope metastases or cause death, while grade 3 tumours had the worst outcome and prognosis. Central, high-grade tumours require aggressive surgical treatment in order to achieve adequate surgical margins, particularly in those lesions located close to the sacroiliac joint. By contrast, grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce operative morbidity, but without reducing survival.

Publisher

British Editorial Society of Bone & Joint Surgery

Subject

Orthopedics and Sports Medicine,Surgery

Reference17 articles.

1. Primary chondrosarcoma of long bones and limb girdles

2. Miller RW, Boice JD Jr, Curtis RE. Bone cancer. In: Schottenfeld D, Fraumeni JF Jr, eds. Cancer epidemiology and prevention. Second edition. New York: Oxford University Press, 1996:971–83.

3. Larsson SE, Lorentzon R. The geographic variation of the incidence of malignant primary bone tumours in Sweden. J Bone Joint Surg [Am] 1974;56-A:592–600.

4. Unni KK. Dahlin’s bone tumors: general aspects and data on 11,087 cases. Fifth ed. Philadelphia: Lippincott-Raven, 1996:71–108.

5. Schajowicz F. Tumor and tumor like lesions of bone: pathology, radiology, and treatment. Second edition. Berlin: Springer-Verlag, 1994:141–244.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3