Hematological Study to Effect Androgen Anabolic steroid (Dianabol) in Female Albino Rats

Author:

Ghani Jenan Mahdi,Hammod Hanan Jassim,Jaffat Haider Salih

Abstract

The present study on the Albino female rats show the effects on blood parameters induced by repeated administration of three doses of androgenic anabolic steroid (dianabol). The animals were divided in to four groups (6 animals for each group). The first group is considered as a negative control treated with diet and water only. Second, third and fourth treatment groups gives orally pendent dianabol (10, 30 and 50) mg/kg/day respectively, and all groups quaff for 6 weeks.The result showed that significant increase`(P less than 0.05) in RBC, WBC count, HB, HG, PCV, lymphocyte, platelet count, and percentage of lymphocyte in treatment groups compared with control. The results refer that significant decrease`(P less than 0.05) in mean corposclar Hemoglobin and concentration (MCHC), while the mean of corpuscular hemoglobin(MCH) and corpuscular volume (MCV) show significant increase `(P less than 0.05) compared with control group.

Publisher

Dr. Yashwant Research Labs Pvt. Ltd.

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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