Inhaled Polymyxin in Treatment of Elderly Patients with Severe Community-Acquired Klebsiella pneumoniae-Induced Pneumonia

Author:

Sakharov V. I.1ORCID,Mironov P. I.2ORCID,Ruslykova I. A.3ORCID,Lutfarakhmanov I. I.2ORCID

Affiliation:

1. G.G. Kuvatov Republican Clinical Hospital

2. Bashkir State Medical University

3. North-Western State Medical University named after I.I. Mechnikov

Publisher

Bashkir State Medical University

Subject

General Engineering,Energy Engineering and Power Technology

Reference15 articles.

1. Kuzovlev A.N., Grechko A.V. Inhaled Antibiotics in Reanimatology: Problem State and Development Prospects (Review). General Reanimatology. 2017;13(5):69–84 (In Russ.). DOI: 10.15360/1813-9779-2017-5-69-84

2. Rello J., Solé-Lleonart C., Rouby J.J., Chastre J., Blot S., Poulakou G., et al. Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. Clin Microbiol Infect. 2017;23(9):629–39. DOI: 10.1016/j.cmi.2017.04.011

3. Kalil A.C., Metersky M.L., Klompas M., Muscedere J., Sweeney D.A., Palmer L.B., et al. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis. 2016;63(5):e61–111. DOI: 10.1093/cid/ciw353

4. Korbila I.P., Michalopoulos A., Rafailidis P.I., Nikita D., Samonis G., Falagas M.E. Inhaled colistin as adjunctive therapy to intravenous colistin for the treatment of microbiologically documented ventilatorassociated pneumonia: a comparative cohort study. Clin Microbiol Infect. 2010;16(8):1230–6. DOI: 10.1111/j.1469-0691.2009.03040.x

5. Tumbarello M., De Pascale G., Trecarichi E.M., De Martino S., Bello G., Maviglia R., et al. Effect of aerosolized colistin as adjunctive treatment on the outcomes of microbiologically documented ventilator-associated pneumonia caused by colistin-only susceptible gram-negative bacteria. Chest. 2013;144(6):1768–75. DOI: 10.1378/chest.13-1018

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