1. hypertension (65�6%, ?2trend p<0�001) and also had a higher mortality rate (18�6%, ?2trend 145 p<0�001) (Figure 2B and 2C);p <0�001)
2. Except for children, the other 152 groups of patients with non-cure had a higher percentage of HIV co-infection (Figure 2D). The most 153 affected group was adults (p=0�013, p?=0), followed by young (p=0�05, p?=0) and elderly people 154 (p=0�006, p?=0) (Figure 2D). Adults and young people with an unfavorable outcome also had higher 155 frequencies of prior TB cases (Figure 2E), both with p=0�007 and p?=0;Anti-TB treatment outcomes over time 147 Over time, the proportion of treatment outcomes did not differ substantially (Table 1), but there was 148 some variability according to age group (Figure 2C, ?2trend p<0�001)
3. maintained a similiar proportion of sex 159 distribution over the years (Table1), as well as the incidence per 100 thousand inhabitants, did not 160 change significantly (Figure 1B);TB in Children 158 Children diagnosed with TB between the years 2010 and 2019
4. Table 1: Participants’ characteristics at pre-treatment including 95% confidence interval (CI 95%).
5. This change was 172 characterized by a significant increase in TB incidence in men over the study period (MK-trend 173 p=0�0007), while the TB incidence in women remained relatively stable (MK-trend p=0�751) (Figure 174 1B). The most common (86�4%) form of TB in young patients was PTB, (appendix p 5) and a high 175 positive smear rate was observed (76�9%, appendix p 5 );Additional factors associated with unfavorable outcomes were 179 male(aOR: 1�18, 95%CI:1�10-1�27, p<0�001), illiteracy (aOR: 1�49, 95%CI:1�31-1�69, p<0�001), HIV 180 infection (aOR: 2�69, 95%CI: 2�35-3�08, p<0�001), illicit drug use