Low Entropic Cost of Binding Confers High Selectivity on an Allosteric ERK2 Inhibitor

Author:

Sugiyama Hajime,Yoshida Mayu,Nagao Haruna,Sawa Masaaki,Kinoshita Takayoshi

Publisher

Elsevier BV

Reference18 articles.

1. Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases;G L Johnson;Science,2002

2. Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation;J M Kyriakis;Physiological Reviews,2001

3. Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention;R Herrera;S27-S31,2002

4. Knowledge-Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery;T Kinoshita;Chemical Biology & Drug Design,2011

5. Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex;M Ohori;Biochemical and Biophysical Research Communications,2005

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