Structural Studies of the uPA-Nafamostat Complexes Reveal a Covalent Inhibitory Mechanism of Nafamostat as the Basis for its Serine Protease Inhibition-Reference-Cited by-同舟云学术

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Structural Studies of the uPA-Nafamostat Complexes Reveal a Covalent Inhibitory Mechanism of Nafamostat as the Basis for its Serine Protease Inhibition

Published:2022 Issue: Volume: Page:
ISSN:1556-5068
Container-title:SSRN Electronic Journal
language:en
Short-container-title:SSRN Journal

Author:

Zhou Yang,Wu Juhong,Li Jinyu,Jiang Longguang,Huang Mingdong

Publisher

Elsevier BV

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference44 articles.

1. Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats;M Iwaki;Jpn J Pharmacol,1986

2. Nafamostat mesilate attenuates colonic inflammation and mast cell infiltration in the experimental colitis;E Y Cho;Int Immunopharmacol,2011

3. Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19;M Hoffmann;Antimicrob Agents Chemother,2020

4. Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition;Y Fujiwara;J Hepatobiliary Pancreat Sci,2011

5. Inhibition of the NF-kappaB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis;Y X Lu;Cancer Lett,2016

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