1. Fr. 02A (2.15 g) was successively fractionated by Sephadex LH-20 CC eluted with CHCl 3 -MeOH (1:1, v/v), RP-C18 (MeOH-H 2 O, 6:1, v/v) to yield compound 6 (4.5 mg). Fr. 02B (1.17 g) was further subjected to silica gel CC (CH 2 Cl 2 -MeOH;g) was separated by silica gel CC with PE-EtOAc (5:1, v/v) to yield three subfractions (02A, 02B and 02C)
2. :1, 5:1 and 1:1, each 500 mL) to yield six subfractions (04A-04F);Fr. 04A (1.51 g) was semipreparative HPLC eluted with MeOH-H 2 O (4:7, v/v), silica gel CC