Complexes of Copper(Ii) with Tetradentate S,O-Ligands: Synthesis, Characterization, Dna/Albumin Interactions, Molecular Docking Simulations and Antitumor Activity

Author:

Živanović Ana S.,Bukonjic Andriana M.,Jovanović-Stević Snežana,Bogojeski Jovana,Ćoćić Dušan,Popović Bijelić Ana,Ratković Zoran R.,Volarević Vladislav,Miloradović Dragana,Tomović Dušan Lj.,Radić Gordana P.

Publisher

Elsevier BV

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference65 articles.

1. This indicates that the complex 494 C1 containing two methylene groups in the side chain of inert ligand shows the highest 495 reactivity, while the least reactive is a complex C4 with five methylene groups. Thus, the 496 introduction of additional methylene groups into the side chain of the inert ligand causes the 497 steric hindrance slowing down the substitution process. Furthermore, by comparing the values 498 of the second-order rate constants for both substitution steps, k 1 and k , the second 499 substitution step is slower than the first one in all studied systems;The obtained results

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