1. on a decentralized list (the "ledger") that is stored in its entirety on many users' computers (so-called "nodes"). 41 New transactions are bundled in blocks of information; they are added to the previous blocks on the ledger through a mathematical process ("mining"); 42 and their authenticity is finally confirmed by the nodes via a decentralized consensus mechanism -creating a list (chain) of transaction blocks. 43 Thereby, the blockchain logs all transactions, or other changes, made to it since its inception in a database accessible from every node;The Functioning of Blockchain-Based Systems Using a public-private key encryption protocol, a blockchain logs pieces of information, such as transactions between two users (for example: a monetary payment)
2. Top row from the left: Knock in in Silkworm, see Daimon et al., 14-25. Knock out in Xenopus laevis, see Suzuki et al., 108-114. Knock out in zebrafish, see Kawahara et al., 26-33. Knock out in medaka, see Kinoshita et al., 98-107. Middle row: Schematic dr
3. Pacing your patients