Impact of Ligand Structure and Base Bead Pore Size on Host Cell Protein Removal During Monoclonal Antibody Purification Using Multimodal Chromatography Resin

Author:

Mori Chigusa,Iwamoto Eri,Kadoi Kenji,Pluskal Malcolm,Matsumoto Yoshihiro

Publisher

Elsevier BV

Reference21 articles.

1. Therapeutic monoclonal antibodies approved by FDA in 2022;H H Cai;Clin. Exp. Immunol,2023

2. Challenges to industrial mAb bioprocessing-Removal of host cell proteins in CHO cell bioprocesses;S Gilgunn;Curr. Opin. Chem. Eng,2018

3. Host cell protein profiling of commercial therapeutic protein drugs as a benchmark for monoclonal antibody-based therapeutic protein development;R Molden;MABS,2021

4. High-risk" host cell proteins (HCPs): A multi-company collaborative view;M Jones;Biotechnol. Bioeng,2021

5. Preparation and characterization of prototypes for multi-modal separation media aimed for capture of negatively charged biomolecules at high salt conditions;B.-L Johansson;J. Chromatogr. A,2003

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