1. (2)�, ? = 77.260 (3)�, ? = 85.667(2)�, V = 907.05 (5) � 3 , Z = 2, ?=1.38 g/cm 3 , ? (Cu K?) = 0.802 mm -1 ; Final R indexes [I>2? (I)]: R 1 = 0.0319 and wR 2 = 0.0830; Final R indexes (all data): R 1 = 0.0603 and wR 2 = 0.0846. Flack Parameters = N;Crystallographic data for 7: orthorhombic crystals (0.22 mm � 0.07 mm � 0.01 mm)
2. Crystallographic data for 8: orthorhombic crystals (0.1 mm � 0.03 mm � 0.01 mm), obtained in a culture solvent of CH 2 Cl 2 -CH 3 OH (1:1, v/v) at 4 �C constant temperature;Flack Parameters = N. CCDC 2243218
3. 836 mm -1 ; Final R indexes [I>2? (I)]: R 1 = 0.0571 and wR 2 = 0.1430; Final R indexes (all data): R 1 = 0.0736 and wR 2 = 0.1567. Flack Parameters = N;CCDC
4. Natural products as sources of new drugs over the nearly four decades from 01;D J Newman;J. Nat. Prod,1981