Global Prevalence of Human Enteric Adenovirus Infections: A Systematic Review and Meta-Analysis

Author:

Wikswo Mary,Kambhampati Anita,Mattison Claire,Chhabra Preeti,Olojo Oluwatosin,Rana Taha,Vinje Jan,Kirkwood Carl,Parashar Umesh D.,Mirza Sara

Publisher

Elsevier BV

Reference48 articles.

1. Pooled prevalence was not statistically different among controls by age, setting, or method of detection. Prevalence of pan-HAdV was statistically different by development index (p=0�0132);�1% For Hadv-F;95% CI 0�9 -4�9; Table 3)

2. There was an insufficient number of studies with non-AGE control data to estimate pooled prevalences of HAdV-F by setting, method of detection, or development index. A total of 104 (65%) studies reported test results for at least one pathogen other than pan-HAdV. Among pan-HAdV positive AGE case-patients, the median proportion of an additional co-detected pathogen was 28% (range 0 -100%). Seven (4%) studies reported test results for at least one pathogen other than pan-HAdV among non-AGE controls. Among non-AGE controls, the median proportion of pan-HAdV positives with a co;LMD countries

3. HAdV-F40 and HAdV-F41 genotyping results were available for 2,629 pan-HAdV positive specimens across 31 (19%) studies. A total of 317 (12%) specimens were typed as HAdV-F40, 1,495 (57%) as HAdV-F41, and 817 (31%) as another HAdV genotype. The proportion of HAdV-F40 and HAdV-F41 varied widely by study; HAdV-F40 was reported for 0% -61% of genotyped HAdVs in each study, and HAdV-F41 was reported for 10% -100% of genotyped HAdVs in each study. No studies reported genotyping data for non-AGE controls;There was insufficient number of studies

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