Polystyrene Microplastic Exposure is Hazardous for Human Placentas

Author:

Sousa Ashelley Alves,Xavier Marques Aldilane Lays,Pires Keyla Silva Nobre,Cavalcante Isadora Hart,Cavalcante Iasmin Lira,Santos Julia Domingues,Queiroz Maiara Cavalcante,Leite Ana Catarina,Crispim Alessandre Carmo,Júnior Edmilson,Aquino Thiago,de Magalhaes Oliveira Lais Farias Azevedo,Souza Samuel,Fonseca Eduardo,Weingrill Rodrigo Barbano,Urschitz Johann,Ospina-Prieto Stephanie,Borbely Alexandre Urban

Publisher

Elsevier BV

Reference54 articles.

1. This underscores the limitations in acquiring MP for research, as the comercial ones are too distant from weathered MP. Dusza and colleagues managed to study Bewo cells exposed to PS-MP and high-density polyethylene, both with different sizes, while also evaluating the in vitro weathering of such MP and their effects on cells compared to pristine MPs. Weathering did not affect MNP internalization, and no cytotoxicity was found after 24-hour treatments;Sarret Larue;Pradas del Real, 2021), and environmental weathering tends to result in an overall negative surface charge,2012

2. Placental chorionic villi metabolism is disrupted by PS-MP exposure Not only did PS-MP cause increased cytotoxicity, oxidative stress, protein carbonylation, and lipid peroxidation, but they also affected the entire placental metabolism, particularly with reduced levels of alanine, formate, glutaric acid, and maltotriose, all of which are connected with the oxidative stress response and mitochondrial dysfunction, disrupting placental metabolism;Rani;Metabolomics,2016

3. Environmental emission, fate and transformation of microplastics in biotic and abiotic compartments: Global status, recent advances and future perspectives;M U Ali;Science of The Total Environment,2021

4. Microplastics incorporated by honeybees from food are transferred to honey, wax and larvae;A M Alma;Environ Pollut,2023

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