A Study of Some Physiological and Biochemical Variables for Patients with Coronary Artery Disease

Abstract

The current study aimed to investigate some physiological and biochemical variables for patients with atherosclerosis of the heart, as some functional and metabolic criteria, and to compare the results of patients with the control group (healthy ones) and the study sample include (120) volunteers whose ages ranged from (30 – 96 years) from the residents of Wasit and Dhi Qar governorates, as data were collected for the samples of the current study to include the age group, where the results of the study sample showed the highest rates of patients within the age group (50-69 years) compared with the control group and for both sexes. Whereas, the laboratory tests of the biochemical-metabolic criteria indicated that there were significant differences in the concentrations of lipids in blood serum samples between the two groups of patients and the control with statistical significance, as the concentrations of lipids increased in each of cholesterol, triglycerides TG, low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL), and a decrease in the level of High-density lipoproteins (HDL) in patients with atherosclerosis compared with the control group for both sexes, in addition, the results of the study showed that significant changes in the levels of the two biomarkers of atherosclerosis, as a significant increase was observed in the levels of OPG and endothelin ET in the serum of atherosclerosis patients of both sexes, compared to the control group, respectively. It is concluded from this study that the changes in serum levels of OPG and endothelin ET, as the results showed that males are more susceptible to atherosclerosis than females, and it also showed that the older the age, the greater the risk factors for atherosclerosis.