Role of Nuclear Factor of Activated T Cells Signaling in the Development of Allergic Rhinitis
Author:
Affiliation:
1. University of Tokushima
2. Kochi National Hospital
3. JA Kochi Hospital
4. Osaka Ohtani University
Publisher
The Society of Practical Otolaryngology
Subject
Otorhinolaryngology
Link
https://www.jstage.jst.go.jp/article/jibirinsuppl/158/0/158_12/_pdf
Reference18 articles.
1. 1) Kitamura Y, Nakagawa H, Fujii T, et al. : Effects of antihistamine on up-regulation of histamine H1 receptor mRNA 24 in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit. J Pharmacol Sci 129: 183–187, 2015.
2. 2) Mizuguchi H, Kitamura Y, Kondo Y, et al. : Preseasonal prophylactic treatment with antihistamines suppresses nasal symptoms and expression of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis. Methods Find Exp Clin Pharmacol 32: 745–748, 2010.
3. 3) Mizuguchi H, Hatano M, Matsushita C, et al. : Repeated pre-treatment with antihistamines suppresses transcriptional up-regulations of histamine H1 receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats. J Pharmacol Sci 108: 480–486, 2008.
4. 4) Furukido K, Takeno S, Ueda T, et al. : Suppression of the Th2 pathway by suplatast tosilate in patients with perennial nasal allergies. Am J Rhinol 16: 329–336, 2002.
5. 5) Shahriar M, Mizuguchi H, Maeyama K, et al. : Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions. J Immunol 183: 2133–2141, 2009.
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