Benzalkonium Salts of Amino Acids – Physicochemical Properties and Anti-Microbial Activity

Author:

Ossowicz Paula1,Janus Ewa1,Błaszak Magdalena2,Zatoń Kinga2,Rozwadowski Zbigniew3

Affiliation:

1. 1Institute of Organic Chemical Technology, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology Szczecin, ul. Pułaskiego 10, 70-322 Szczecin, Poland

2. 2Department of Chemistry, Microbiology and Environmental Biotechnology, Faculty of Environmental Management and Agriculture, West Pomeranian University of Technology in Szczecin, ul. Słowackiego 17, 71-434 Szczecin, Poland

3. 3Department of Inorganic and Analytical Chemistry, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology Szczecin, Al. Piastów 42, 70-065 Szczecin, Poland

Abstract

AbstractNew salts combining a benzalkonium cation and chiral amino acid anions were synthesized and characterized. The identification was performed by NMR spectroscopy. Properties such as temperature of phase transformation, specific rotation, thermal stability and surface activity and antimicrobial activity were determined and compared with that of benzalkonium chloride. Benzalkonium amino acids salts can be used as conditioners in cosmetics. It has been shown they have weak impact on symbiotic microorganisms which occupy a wide range of skin, and this confirms that they do not disturb the biological balance of human skin.

Publisher

Walter de Gruyter GmbH

Subject

Condensed Matter Physics,General Chemical Engineering,General Chemistry

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