Determination of 89Zr production parameters via different reactions using ALICE and TALYS codes

Abstract

Abstract 89Zr is an important positron-emitting radionuclide for positron emission tomography (PET) and used in the field of tumor diagnostics, tumor therapy and the investigation of the bio-kinetic. The ALICE-91 and TALYS-1.0 codes were used to calculate excitation function for proton, alpha, deuteron and neutron induced on various targets that lead to the production of 89Zr radioisotopes using intermediate energy accelerators. Requisite thickness of the targets was obtained by SRIM code. The 89Zr production yield was evaluated using excitation function and stopping power. For the 89Y(p, n)89Zr reaction, the calculation data were compared with the experimental data. The 89Y(p, n)89Zr process was determined as most interesting one due to radionuclide purity. The ALICE-91 and TALYS-1.0 codes predict a maximum cross-section of about 939.86 mb at 15MeV and 860 mb at 13MeV respectively for this reaction.