A Review on Fast Dissolving Tablets

Abstract

Fast dissolving tablet (FDT) is one such type of an innovative and unique drug delivery system which is swiftly gaining much attention in the research field of rapid dissolving technology. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for paediatric and geriatric patients. Fast dissolving Tablets are disintegrating and/or dissolve rapidly in the saliva without the need for water. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast-dissolving tablets. FTD contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fastdisintegrating tablets, as they may take up to a minute to completely disintegrate. FDTs formulations contain super disintegrants to enhance the disintegration rate of a tablet in the buccal cavity. This review describes the various advantages, limitations, desired characteristics, formulation aspects, super-disintegrate employed, technologies developed for FDTs, novel hole technology, evaluation tests, drugs used in fast dissolving tablets, marketed formulations and patented drugs.