A Comparative Study of Fluoride Containing Chlorhexidine and Non-Chlorhexidine Mouthrinses in a Teenage Group

Abstract

Aim: The study was planned to assess the effect of a mouthrinse containing Chlorhexidine (CHX) and amine/stannous fluoride (AmF) on plaque accumulation, gingivitis and salivary fluoride levels in comparison with two mouthrinses containing either essential oils (EO) or cetylpyridinium chloride (CPC) with sodium fluoride (NaF) in a teenage group. Methodology: For this study 82 healthy teenage between 13 and 16 years were recruited for participation. The experimental gingivitis model consisted of a 2-weeks recruitment phase, followed by a 6-day rinsing period with one of the 4 mouthrinse formulations was used for the study. At the end of the pre-phase period and the rinsing period (Day-0/Day-6), gingival index (GI), plaque index (PI) and salivary fluoride levels were recorded. The statistical analyses were performed using Wilcoxon sign test  and the dependent t test. Results: A reduction in plaque re-growth was seen for the CHX+AmF formulation rinse, although there were no significant differences among all groups (p>0,001). During the experimental periods, the gingivitis indices increased significantly for all formulations (p<0,001), except for the CHX+AmF formulation. The CHX+AmF formulation scored higher levels of salivary fluoride at the end of the rinsing period (p>0,001). Conclusion: It reveals that the adjunctive use of AmF containing CHX mouthrinses to mechanical oral hygiene should be recommended for teenage at risk groups.  How to cite this article: Atabek D, Alaçam A, Çakılcı B, Berkkan A. A Comparative Study of Fluoride Containing Chlorhexidine and Non-Chlorhexidine Mouthrinses in a Teenage Group. Int Dent Res 2012;1:1-7. Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.