Hypogammaglobulinaemia and lipaemia initiated by the murine sarcoma virus (Moloney) in rats

Abstract

Chemical and electrophoretic studies of serum obtained from rats bearing tumours induced by murine sarcoma virus (Moloney) revealed a substantial drop in γ-globulin level and, to a lesser degree, in the albumin level. The α-1 and α-2 globulin fraction levels rose sharply. Also elevated were serum total fatty acids, serum cholesterol levels, lipoprotein (almost entirely associated with the β-lipoprotein and chylomicrons fractions) and the serum glutamic oxalacetic transaminase level.