Refinement and reduction in production of genetically modified mice

Author:

Robinson V.1,Morton D. B.2,Anderson D.3,Carver J. F. A.4,Francis R. J.5,Hubrecht R.6,Jenkins E.7,Mathers K. E.4,Raymond R.8,Rosewell I.8,Wallace J.9,Wells D. J.10

Affiliation:

1. Research Animals Department, RSPCA, Wilberforce Way, Southwater, West Sussex RH13 7WN, UK (To whom all correspondence should be addressed)

2. Biomedical Services Unit, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

3. Home Office, Constitutional & Community Policy Directorate, PO Box 6779, Dundee DD1 9WN, UK

4. MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK

5. The Medical School, University of Bristol, University Walk, Bristol BS18 1TD, UK

6. UFAW, The Old School, Brewhouse Hill, Wheathampstead, Herts AL4 8AN, UK

7. FRAME, Russell & Burch House, 96–98 North Sherwood Street, Nottingham NG1 4EE, UK

8. Cancer Research UK, London Research Institute, Clare Hall Laboratories, South Mimms EN6 3LD, UK

9. McElwain Laboratories, Institute of Cancer Research, 15 Cotswold Rd, Sutton, Surrey SM2 5NG, UK

10. Gene Targeting Unit, Department of Neuromuscular Diseases Division of Neuroscience & Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, St Dunstan's Road, London W6 8RP, UK

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

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