Finding cases of Trichomonas vaginalis infection in England

Author:

Mahto M1,Evans-Jones J2,Zia S1,Robinson T I3,Rothburn M M3,Mallinson H3

Affiliation:

1. East Cheshire NHS Trust, Macclesfield District General Hospital, Macclesfield

2. Countess of Chester Hospital NHS Foundation Trust, Chester

3. University Hospital Aintree NHS Foundation Trust, Liverpool, UK

Abstract

We describe the use of a new molecular assay for Trichomonas vaginalis (TV), the Gen-Probe Aptima TV (ATV) in female attendees at community clinics, a genitourinary (GU) medicine clinic and a prison GU medicine service. Positivity rates at community clinics and GU medicine were 0/382 (0%) and 3/358 (0.8%, 95% confidence interval [CI] 0–1.7%), respectively. Positivity was significantly higher, 29/269 (10.8%, 95% CI 7.1–14.5%), odds ratio (OR) 14.3 (4.11 < OR < 59.55), in those tested at the prison. A questionnaire survey of English GU medicine clinics and data from the UK Health Protection Agency (HPA) for England both demonstrated the large variation in case rates by region and testing methods employed. Higher rates were seen in women, in prison GU medicine services and in London GU medicine clinics. The ATV assay is now CE-marked (Conformité Européenne) and so a larger prospective study of its potential application is warranted.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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