Ultrastructural studies of chronic pneumonia in guineapigs

Author:

Baskerville A.1,Dowsett A. B.1,Baskerville Margaret2

Affiliation:

1. Public Health Laboratory Service, Centre for Applied Microbiology & Research, Parton Down, Salisbury, Wiltshire, United Kingdom

2. Chemical Defence Establishment, Parton Down, Salisbury, Wiltshire, United Kingdom

Abstract

Pulmonary interstitial fibrosis commenced as focal proliferation of fibroblasts and accumulation of macrophages in interalveolar septa and was followed by deposition of excess collagen. Epithelium of airways and alveoli remained normal. Perivascular nodules of lymphoid tissue which developed in the lungs of many older animals had a high mitotic rate, but the lymphocytes were morphologically normal. Micro-organisms were not observed in the lungs of any animal.

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Non-Infectious Diseases;The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents;2012

2. The toxicity of a red phosphorus smoke after repeated inhalation;Journal of Hazardous Materials;1989-12

3. An Ultrastructural Study of Spontaneous Chronic Lung Lesions in Asymptomatic Rabbits;Journal of Veterinary Medicine Series A;1989-02-12

4. Repeated dose inhalation toxicity of cinnamic acid smoke;Journal of Hazardous Materials;1989-01

5. Correlation of ultrastructure of the air-blood barrier and surfactant activity;Bulletin of Experimental Biology and Medicine;1988-11

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