A survey of the pathology of marmosets (Callithrix jacchus) derived from a marmoset breeding unit

Author:

Chalmers D. T.1,Murgatroyd L. B.2,Wadsworth P. F.2

Affiliation:

1. Imperial Chemical Industries PLC, Pharmaceuticals Division, Safety of Medicines Department, Alderley Park, Macclesfield, Cheshire, United Kingdom; Imperal Chemical Industries PLC, Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, UK

2. Imperial Chemical Industries PLC, Pharmaceuticals Division, Safety of Medicines Department, Alderley Park, Macclesfield, Cheshire, United Kingdom

Abstract

The results of a survey of the major pathological conditions encountered in an established breeding colony of common cotton-eared marmosets ( Callithrix jacchus) is presented. 265 home-bred and 70 imported wild-caught marmosets were examined. A Heinz body haemolytic anaemia and skeletal muscle myopathy were the most common pathological findings and were considered to be a result of a complex nutritional deficiency involving vitamin E, selenium and protein. Inflammatory disease of the intestinal tract was also a major feature. Chronic colitis was particularly common in older marmosets. Pneumonia, otitis media, meningitis and brain abscesses were important pathological findings in home-bred marmosets and were commonly associated with bacterial infections, particularly Bordetella bronchiseptica and Klebsiella species. Trichospirura leptostoma within pancreatic ducts of wild-caught marmosets was the only significant parasitic disease encountered. Mycotic infections of the upper alimentary tract with Candida species were occasional findings in debilitated animals. No pathological features suggesting viral diseases were found.

Publisher

SAGE Publications

Subject

General Veterinary,Animal Science and Zoology

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