Affiliation:
1. Imperial Chemical Industries Ltd, Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, United Kingdom
Abstract
A conventional diet fed to rats in an agar-gel base reduced mature body weight by about 25% and increased longevity when compared to the same diet in pelleted form. Dry matter intake was not affected, but food utilization was considerably poorer. The use of a diet in agar gel may, therefore, provide an improved toxicological assay, especially when used in combination with flushing racks housing 2 animals per cage, where exposure of the animal technician to dust was reduced.
Subject
General Veterinary,Animal Science and Zoology
Cited by
8 articles.
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