Unilateral penile swelling: an unusual presentation of primary syphilis?

Abstract

Summary: Primary syphilis is characterized by a solitary, painless, indurated ulcer (chancre) at the site of inoculation, with associated inguinal lymph nodes that are enlarged, rubbery, painless and discrete. We report a case of syphilis that presented with penile swelling associated with tender lymphadenopathy and review the literature concerning this unusual presentation of early syphilis.