Imiquimod use in the genital area and development of lichen sclerosus and lichen planus-Reference-Cited by-同舟云学术

Imiquimod use in the genital area and development of lichen sclerosus and lichen planus

Published:2010-03 Issue:3 Volume:21 Page:219-221
ISSN:0956-4624
Container-title:International Journal of STD & AIDS
language:en
Short-container-title:Int J STD AIDS

Author:

O'Mahony C¹,Yesudian P D¹,Stanley M²

Affiliation:

1. Countess of Chester Hospital NHS Foundation Trust, Chester CH2 1UL

2. Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK

Abstract

Imiquimod has immune-stimulant properties that can precipitate autoimmune conditions like eczema, psoriasis and lichenoid conditions. We report two cases here where imiquimod induced florid lichen sclerosus in one patient and lichen planus in another. In both patients the condition was so aggressive and unresponsive to steroid treatment that circumcision was necessary.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Link

http://journals.sagepub.com/doi/pdf/10.1258/ijsa.2009.009154

Reference8 articles.

1. Difficult wart cases - use of imiquimod cream 5%

2. The Role of Toll-like Receptors in the Pathogenesis and Treatment of Dermatological Disease

3. A case of severe eczema following use of imiquimod 5% cream

4. Interferon α-Inducible Protein 27 (IFI27) is Upregulated in Psoriatic Skin and Certain Epithelial Cancers

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