Choriocarcinoma in an AIDS patient – relapsing but not fatal

Author:

Shah Archan M1,Tidswell Mark1,Prefontaine Michel2,Skiest Daniel J1,Pantanowitz Liron3

Affiliation:

1. Department of Medicine, Baystate Medical Center, Tufts University School of Medicine, 759 Chestnut Street – S2570, Springfield, MA 01199

2. Department of Gynecologic Oncology

3. Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA

Abstract

Summary Choriocarcinoma is associated with high mortality in immunocompromised patients, in contrast to a good prognosis in immunocompetent individuals. Respiratory failure due to metatstatic choriocarcinoma is associated with high mortality in any patient. We report a case of a woman with AIDS that survived metastatic choriocarcinoma and respiratory failure. We also observed that in contrast to some in vitro studies, the markedly elevated levels of β-subunit of human chorionic gonadotropin in this patient did not have any apparent inhibitory effect on viral replication.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

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