Depression associated with antiretroviral drug therapy in HIV: case report and overview-Reference-Cited by-同舟云学术

Depression associated with antiretroviral drug therapy in HIV: case report and overview

Published:2012-06 Issue:6 Volume:23 Page:e14-e19
ISSN:0956-4624
Container-title:International Journal of STD & AIDS
language:en
Short-container-title:Int J STD AIDS

Author:

Kaestner F¹,Anneken K²,Mostert C¹,Reichelt D³,Rothermundt M¹,Evers S²,Husstedt I W²

Affiliation:

1. Department of Psychiatry

2. Department of Neurology

3. Department of Internal Medicine D, University of Muenster, Albert-Schweitzer-Str. 11, D-48129 Muenster, Germany

Abstract

Depression is the main psychiatric symptom in patients living with HIV. Genetic predisposition, stress from disease as well as the antiretroviral therapy itself are discussed as pathogenic factors. We report a 35-year-old HIV-positive man suffering from bipolar disorder who developed major depression shortly after commercing combination antiretroviral therapy (cART) on three occasions. The first two times the patient ceased therapy autonomously, and the depression disappeared completely. The close connection between cART and major depression in the present case supports the depression-inducing potential of cART. Additionally, we present an overview of literature.

Publisher

SAGE Publications

Subject

Infectious Diseases,Pharmacology (medical),Public Health, Environmental and Occupational Health,Dermatology

Link

http://journals.sagepub.com/doi/pdf/10.1258/ijsa.2009.009451

Reference58 articles.

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