Methods of Experimental Modeling of Metastasis-Reference-Cited by-同舟云学术

Methods of Experimental Modeling of Metastasis

Published:2021-12-06 Issue:4 Volume:17 Page:44-49
ISSN:2713-0428
Container-title:Journal Biomed
language:
Short-container-title:BIOMEDICINE

Author:

Timofeeva N. Yu.¹,Bubnova N. V.¹,Struchko G. Yu.¹,Kostrova O. Yu.¹,Stomenskaya I. S.¹

Affiliation:

1. I. N. Ulyanov Chuvash State University

Abstract

One of the main problems of modern medicine is cancer, which is the second leading cause of death after cardiovascular disease. Malignant neoplasms have been known for a long time; however, their study still presents signiﬁcant difﬁculties. Modeling of malignant processes in animals allow researchers to study tumors and the main patterns of malignant growth characteristic of animals and humans. The main cause of death in malignant neoplasms is the process of metastasis formation, which remains to be understood in detail. The study of metastatic processes is one of the most important tasks of oncology. To this end, various models of tumor metastasis are created. The article reviews literature data on the most popular models of metastasis in experimental conditions. The advantages and disadvantages of the main approaches to modeling metastasis are evaluated.

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

Reference24 articles.

1. Kit O.I., Frantsiyants E.M., Kaplieva I.V., Trepitaki L.K., Evstratova O.F. Sposob polucheniya metastazov pecheni v eksperimente [Method for obtaining liver metastases in an experiment]. Bulletin of Experimental Biology and Medicine. 2014;6:745–747. (In Russian).

2. Kozlova M.B., Frantsiyants E.M., Trepitaki L.K., Kaplieva I.V., Pogorelova Yu.A., Sergost’yants G.Z., Airapetova T.G., Chubaryan A.V. Rol’ pola v kharaktere sistemnykh i tkanevykh narushenii gormonal’nogo gomeostaza u krys s eksperimental’noi model’yu metastazirovaniya v legkie [The role of gender in the nature of systemic and tissue disorders of hormonal homeostasis in rats with an experimental model of lung metastasis]. Meditsinskii vestnik Severnogo Kavkaza [Medical Bulletin of the North Caucasus]. 2016;3:377–380. (In Russian).

3. Latserus L.A., Pinigina N.M., Kozlov A.M., Baryshnikov A.Yu. Vliyanie preparata Abisilin na protsess iskusstvennogo retsidivirovaniya i metastazirovaniya kartsinomy legkogo L’yuis myshei [The inﬂuence of the drug Abisilin the process of artiﬁcial recurrence and metastasis of lung carcinoma Lewis mice]. Russian Biotherapeutic Journal. 2010;1:29–33. (In Russian).

4. Moskvichev E.V., Struchko G.Yu., Merkulova L.M., Kostrova O.Yu. Morfologiya raka tolstoi kishki posle primeneniya 1,2-dimetilgidrozolin degidrokhlorida [Morphology of colon cancer after the use of 1,2-dimethylhydrazine dihydrochloride]. Vestnik novykh meditsinskikh tekhnologii [Bulletin of New Medical Technologies]. 2009;S2:121–122. (In Russian).

5. Struchko G.Yu., Merkulova L.M., Moskichev E.V., Mikhailova M.N., Kostrova O.Yu., Stomenskaya I.S. Morfofunktsional’noe sostoyanie timusa v usloviyakh razvitiya opukholi tolstoi kishki [Morphofunctional state of the thymus in the conditions of colon tumor development]. Zdravookhranenie Chuvashii [Chuvashia Healthcare Journal]. 2009;3:47–52. (In Russian).

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tumor models in cancer research;P.A. Herzen Journal of Oncology;2024

2. <i>In vivo</i> models in cancer research;Advances in Molecular Oncology;2023-07-10