Discriminant Analysis of the Coordinated Work Indicators of the Heart and Blood Vessels in Health and Disease-Reference-Cited by-同舟云学术

Discriminant Analysis of the Coordinated Work Indicators of the Heart and Blood Vessels in Health and Disease

Published:2021-06-26 Issue:2 Volume:17 Page:8-21
ISSN:2713-0428
Container-title:Journal Biomed
language:
Short-container-title:BIOMEDICINE

Author:

Karkischenko N. N.¹,Chaivanov D. B.²,Chudina Y. A.²,Nikolaev A. A.²,Vartanov A. A.²

Affiliation:

1. Scientifi c Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia

2. National Research Center “Kurchatov Institute”

Abstract

A discriminant method was proposed for modeling and quantifying the consistency of regulatory mechanisms in the cardiovascular system (CVS) of apparently healthy volunteers and those suffering from circulatory disorders associated with cervical spine osteochondrosis (OCS) and somatoform autonomic dysfunction (SAD). The congruence of the parameters of ECG intervalometry (DCI) and pulse wave duration (PWD) according to the volunteers’ photoplethysmograms (PPG) was established by calculating the disparity measure and deviations from the mean values using the coeffi cients of displacement, slope of the approximating straight line, as well as by comparing the reliability and correlation of the trend model with the initial data. We discovered gross violations of congruence in the work of efferent and afferent regulatory CVS mechanisms, mismatch and decrease in comparison with the norm of DCI and PWD, a signifi cant decrease in their approximation in the SAD volunteers. In volunteers with OCS, deviations in DCI and PWD from their mean values are much lower than in those with SAD, being inferior compared to healthy volunteers. Similar to SAD, these patients are inferior to healthy volunteers in terms of the disparity measure.

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

Reference19 articles.

1. Antonen E.G., Hyajnikyajnen I.V. Somatoformnaya vegetativnaya disfunkciya kak prediktor hronicheskoj ishemii mozga [Somatoform autonomic dysfunction as a predictor of chronic brain ischemia]. Uchenye zapiski Petrozavodskogo gosudarstvennogo universiteta. Medicinskie nauki [Scientiﬁ c notes of Petrozavodsk state University. Medical science]. 2014;4:43–48. (In Russian)].

2. Babchenko N.V. Nachal’nye proyavleniya nedostatochnosti krovosnabzheniya golovnogo mozga: patomorfologiya, klinika, diagnostika, principy terapii [Initial manifestations of insufﬁ cient blood supply to the brain: pathomorphology, clinic, diagnosis, principles of therapy]. Medicinskie novosti [Medical news]. 2004;1:17–20. (In Russian)].

3. Boytsov S.A., Nikulina N.N., Yakushin S.S., Akinina S.A., et al. Vnezapnaya serdechnaya smert’ u bol’nykh IBS: po rezul’tatam rossiyskogo mnogotsentrovogo epidemiologicheskogo issledovaniya zabolevayemosti, smertnosti, kachestva diagnostiki i lecheniya ostrykh form IBS (rezonans) [Sudden cardiac death in patients with coronary artery disease: according to the results of a Russian multicenter epidemiological study of morbidity, mortality, quality of diagnosis and treatment of acute forms of coronary artery disease (resonance)]. Russian cardiological journal. 2011;2:59–64. (In Russian)].

4. Bokeriya L.A., Revishvili A.Sh., Neminushchiy N.M. Vnezapnaya serdechnaya smert’ [Sudden cardiac death]. Moscow: GEOTARMedia Publ., 2011: 272. (In Russian)].

5. Karkischenko N.N. Lekarstvennaya proﬁ laktika [Medicinal prophylaxis]. Moscow: Voyentekhlit Publ., 2001:752. (In Russian)].