Study into the Efficacy of the Epophen Substance in Normobaric Hypoxia-Reference-Cited by-同舟云学术

Study into the Efficacy of the Epophen Substance in Normobaric Hypoxia

Published:2023-06-10 Issue:2 Volume:19 Page:45-53
ISSN:2713-0428
Container-title:Journal Biomed
language:
Short-container-title:BIOMEDICINE

Author:

Ostrenko K. S.¹,Ovcharova A. N.¹,Yegorova O. P.²

Affiliation:

1. All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition — Branch of the Federal Scientific Center of Animal Husbandry — The All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst

2. Scientific and Production Company “IGLESIA”

Abstract

Hypoxia is associated with reduced oxygen levels in the body, individual organs, or tissues. Hypoxia is the most common cause of cell damage, emerging under a lack of oxygen in the inhaled air, blood (hypoxemia), or tissues (violations of tissue respiration). When the strength or duration of hypoxic exposure exceeds the adaptive capabilities of the body, an organ, or a tissue, irreversible changes may develop. Resistance to hypoxia can be enhanced by pharmacological agents that improve oxygen delivery and/or the effectiveness of its use. This study was conducted to determine the antihypoxic effect of the Epophen drug. Epophen was found to exhibit a pronounced antihypoxic effect, with the efficacy varying from 24 to 89% depending on the drug dose and hypoxia type.

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

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