Pharmacological optimization of premedication to reduce the risk of cardiovascular complications

Author:

Safronenko A. V.1,Maklyakov Yu. S.1,Lepyavka S. V.1,Demidov I. A.1,Demidova A. A.1,Dubatova I. V.1

Affiliation:

1. Rostov State Medical University of the Ministry of Health Сare of Russia

Abstract

In 46 patients with arterial hypertension, arrhythmias and amiodarone-associated type I thyrotoxicosis, it was confirmed that prolonged premedication with long-acting benzodiazepines and magnesium preparations reduces the risk of cardiovascular complications and instability of systemic hemodynamics, mitigates the adverse effects of amiodarone dysfunction of the thyroid gland on the cardiovascular system. Postoperatively, under prolonged premedication with long-acting benzodiazepines and magnesium preparations, postoperative cardiac arrhythmias were found to be less common. When the pre-operative period was significantly reduced, the appointment of long-acting benzodiazepines had advantages over short-acting benzadiazepines due to the prevention of cardiac arrhythmias and increased blood pressure in the early post-operative period. 

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

Reference9 articles.

1. Badikova K.A., Zhenilo V.M., Demidova A.A., Lebedeva E.A., Badikov V.V. Sposob snizheniya psikhoemotsional’nogo napryazheniya pered operativnym vmeshatel’stvom na shchitovidnoy zheleze putem individual’nogo podbora premedikatsii [A method of reducing psycho-emotional stress before surgery on the thyroid through individual premedication selection]. Invention patent RU 2724483 C1, 2020. (In Russian).

2. Badikova K.A., Zhenilo V.M. Vliyanie sedativnogo komponenta premedikatsii, dostigaemogo primeneniem gidroksizina gidrokhlorida, na psikhovegetativnyy i gormonal’nyy status u patsientov s zabolevaniyami shchitovidnoy zhelezy [The effect of the sedative component of premedication achieved by the use of hydroxyzine hydrochloride on psychovegetative and hormonal status in patients with thyroid diseases]. Vestnik anesteziologii i reanimatologii [Anesthesiology and Resuscitation Bulletin]. 2017;14(1):24–28. (In Russian).

3. Vorobiev K.P., Mitrokhin K.V. Izmeneniya vegetativnoy regulyatsii na etapakh predoperatsionnoy podgotovki i posle intubatsii trakhei u patsientov obshchekhirurgicheskogo profilya [Changes in autonomic regulation at the stages of preoperative preparation and after tracheal intubation in general surgical patients]. Vestnik SanktPeterburgskogo universiteta. Seriya Meditsina [St. Petersburg University Bulletin. Series Medicine]. 2018;13(1):5–15. (In Russian). DOI: 10.21638/11701/spbu11.2018.101.

4. Kitiashvili I.Z., Salo A.A., Kitiashvili D.I., Voinova V.I. Vybor optimal’nogo komponenta premedikatsii v khirurgicheskoy praktike [Selection of the optimal component of premedication in the surgical practice]. Mat-ly nauch.-obraz. konf. “Aktual’nye voprosy i innovatsionnye tekhnologii v anesteziologii i reanimatologii” [Proceedings of the scientific and educational conference “Topical issues and innovative technologies in anesthesiology and resuscitation”]. Obshchestvennaya organizatsiya “Chelovek i ego zdorov’e” Publ. 2018:80–81. (In Russian).

5. Orekhova E.S., Gulyaev D.A., Savvina I.A. Personifitsirovannyy podkhod k vyboru premedikatsii u patsientov neyrokhirurgicheskogo profilya [Personalized approach to the choice of premedication in neurosurgical patients]. Anesteziologiya i reanimatologiya [Anesthesiology and Resuscitation]. 2019;3:79–89. (In Russian). DOI: 10.17116/anaesthesiology201903179.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3